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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPS6KA4
All Species:
3.64
Human Site:
S758
Identified Species:
5.33
UniProt:
O75676
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75676
NP_001006945.1
772
85606
S758
P
G
R
A
P
V
A
S
K
G
A
P
R
R
A
Chimpanzee
Pan troglodytes
XP_508900
901
98668
A887
P
G
R
A
P
V
A
A
K
G
A
P
R
R
A
Rhesus Macaque
Macaca mulatta
XP_001114877
772
85557
A758
P
G
R
A
P
T
A
A
K
G
A
P
R
R
A
Dog
Lupus familis
XP_854926
772
85603
A758
A
Q
G
R
A
P
A
A
K
G
A
P
R
R
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2B9
773
85721
A758
S
G
R
L
P
A
S
A
A
K
G
T
T
R
R
Rat
Rattus norvegicus
Q63531
735
82865
S720
Q
L
K
P
I
E
S
S
I
L
A
Q
R
R
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506738
716
80894
G689
S
S
S
S
H
S
H
G
K
T
T
P
T
K
T
Chicken
Gallus gallus
Q5F3L1
789
89022
G762
S
S
S
S
H
S
H
G
K
T
T
P
T
K
T
Frog
Xenopus laevis
P10665
733
82620
S718
L
L
Q
P
I
K
S
S
I
L
A
Q
R
R
V
Zebra Danio
Brachydanio rerio
Q6PFQ0
740
83378
Q727
V
A
A
S
S
L
A
Q
R
R
N
M
K
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3I5
1207
137026
E1182
Q
L
K
R
T
K
R
E
P
K
V
P
R
P
P
Honey Bee
Apis mellifera
XP_395099
910
102507
R889
C
T
S
H
V
D
F
R
E
I
H
R
K
Q
K
Nematode Worm
Caenorhab. elegans
Q18846
772
87050
N759
M
M
N
Y
R
E
P
N
S
G
T
I
R
E
T
Sea Urchin
Strong. purpuratus
XP_786494
918
102561
E730
S
Q
S
S
S
S
Q
E
S
T
T
P
T
P
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39030
471
53019
R458
F
T
N
F
T
Y
V
R
P
P
H
S
F
L
H
Baker's Yeast
Sacchar. cerevisiae
P18961
677
76646
E664
G
W
T
Y
I
G
D
E
Q
L
G
D
S
P
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.4
98.6
96.7
N.A.
95.8
41.3
N.A.
56
64
41
41.9
N.A.
27
45.1
48.1
48.2
Protein Similarity:
100
85.6
98.9
98
N.A.
96.7
60.6
N.A.
71.6
78.4
59
60.3
N.A.
38.9
60.1
64.3
61.8
P-Site Identity:
100
93.3
86.6
53.3
N.A.
26.6
26.6
N.A.
13.3
13.3
26.6
6.6
N.A.
13.3
0
13.3
6.6
P-Site Similarity:
100
100
93.3
60
N.A.
40
40
N.A.
26.6
26.6
40
40
N.A.
20
20
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.4
21.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.6
37.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
7
19
7
7
32
25
7
0
38
0
0
0
25
% A
% Cys:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
7
7
0
0
0
0
7
0
0
0
% D
% Glu:
0
0
0
0
0
13
0
19
7
0
0
0
0
7
0
% E
% Phe:
7
0
0
7
0
0
7
0
0
0
0
0
7
0
0
% F
% Gly:
7
25
7
0
0
7
0
13
0
32
13
0
0
0
0
% G
% His:
0
0
0
7
13
0
13
0
0
0
13
0
0
0
7
% H
% Ile:
0
0
0
0
19
0
0
0
13
7
0
7
0
0
0
% I
% Lys:
0
0
13
0
0
13
0
0
38
13
0
0
13
19
7
% K
% Leu:
7
19
0
7
0
7
0
0
0
19
0
0
0
7
7
% L
% Met:
7
7
0
0
0
0
0
0
0
0
0
7
0
0
0
% M
% Asn:
0
0
13
0
0
0
0
7
0
0
7
0
0
0
0
% N
% Pro:
19
0
0
13
25
7
7
0
13
7
0
50
0
19
7
% P
% Gln:
13
13
7
0
0
0
7
7
7
0
0
13
0
7
0
% Q
% Arg:
0
0
25
13
7
0
7
13
7
7
0
7
50
44
7
% R
% Ser:
25
13
25
25
13
19
19
19
13
0
0
7
7
0
7
% S
% Thr:
0
13
7
0
13
7
0
0
0
19
25
7
25
0
25
% T
% Val:
7
0
0
0
7
13
7
0
0
0
7
0
0
0
13
% V
% Trp:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
13
0
7
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _